American ginseng and St. John's wort might DECREASE warfarin's anticoagulant effects

October 2004

New research suggests that American ginseng and St. John's wort might DECREASE warfarin's anticoagulant effects.

This is a surprise. Ginseng and many other herbs have antiplatelet effects and were thought to PROLONG bleeding.

But American ginseng (Panax quinquefolius) and St. John's wort seem to REDUCE warfarin's efficacy...possibly by increasing warfarin metabolism.

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